How are the uses of shared data collections evolving in daily scientific work practices? Data repositories for neuroscience are being designed to bring together complex and disparate data to solve questions about the relationships between structure and function in nervous system processes. Successful use of these repositories will require that experiments be documented and data represented to a much greater extent than descriptions in traditional publications. This study investigates how neuroscientists are conducting their data management practices with regard for sharing that data. This poster will present preliminary data on the work involved in depositing data into and using a neural cell image repository. This will include an initial comparison of the kinds of information depositors and users say that they require to interpret the data sets. Studying research documentation activities in daily scientific work may lead to enhancements in local archival practices and aid in the design of tools to support these activities.