Dramatic change in scientific research practice is underway. Computers are commonplace. High-speed networks that bring terms such as teraflop and petabyte to conversations regarding data and computational resources are making e-science a reality. New levels and global partnerships of collaborative work are taking place thanks to this terascale-ready infrastructure. What do these cyberinfrastructures mean for the conduct of science? What implications do these changes have for the management, organization, access, and preservation of scientific and technical information?